How Tadalafil Works To Rectify Sexual Difficulty In Men: When You Don't Want To Keep Your Partner Waiting

Written by the UPGUYS Editorial Team

Published on May 26, 2022

When things get hot and heavy in the bedroom with your partner, the last thing you want to happen is a case of erectile dysfunction.

For many men, this can be embarrassing and stressful.

Don't worry — if you've ever experienced this, you're not alone. 1 in 10 men is estimated to have had ED at some point in their lifetime.

The good news is that there are options available that can help you take back control of the bedroom.

One of those options is tadalafil.

Read this article to learn everything you need to know about how tadalafil works. We'll discuss:

• What is Tadalafil?
• How Tadalafil Works
• How Long Does It Take for Tadalafil to Work?
• Does Tadalafil Have Any Side Effects?
• Who Can and Can't Take Tadalafil?
• Frequently Asked Questions About Tadalafil
• Key Takeaways

Let's dive in.

What Is Tadalafil?

Tadalafil is a commonly used generic prescription medication used to treat impotence or erectile dysfunction (ED), as well as benign prostatic hyperplasia (BPH).

You may know it by its more popular brand name: Cialis.

Interestingly, tadalafil was once studied as a possible treatment for hypertension. The discovery of its effect on penile blood vessels was a complete accident.

You can read more about mixing tadalafil and alcohol here.

How Tadalafil Works

Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. As the name suggests, it prevents an enzyme called phosphodiesterase type-5 from working actively in the body, specifically in the penis.

Erectile dysfunction is a condition where a man's penis doesn't harden when he is sexually stimulated or can't maintain an erection for an extended period of time. 

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Usually, the normal response from the body is to increase blood flow to the penis to create an erection.

The main tadalafil mechanism of action is the PDE5 inhibitors' function of increasing blood flow to the penis by blocking a specific enzyme in the blood vessels. 

Imagine the blood vessels "relaxing," which allows more blood to flow to a specific area quickly. Typically, you'll need physical action to the penis to "activate" an erection. 

You can read more about the causes and solutions for erectile dysfunction here.

How Long Does It Take for Tadalafil to Work?

When you suddenly find yourself needing that extra "help," the biggest question on your mind is probably:

How long does tadalafil take to work for erectile dysfunction?

It usually takes around 30 to 60 minutes for tadalafil to start working. You can take the pill once a day, as soon as 30 minutes before you plan on having sex.

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Tadalafil is a prescription medication. Do not take this medication or increase its dosage on your own.

Again, just taking the pill won't cause an erection on its own. You need to become sexually aroused with physical touch for it to work.

The effects of tadalafil can last anywhere from 24 to 36 hours, which is significantly longer than the competing drug sildenafil (Viagra). Sildenafil only lasts 4 hours.

(Whether this is a good thing or a bad thing is up to you.)

Does Tadalafil Have Any Side Effects?

Like most medications, there are risks to taking tadalafil. It's important to always consult a doctor before taking any medication. Tadalafil is no different.

Most people experience few to no side effects, but some of the most commonly reported side effects include:

• Sickness
• Diarrhea
• Pain in the stomach, legs, arms, or back
• Stuffy nose and cough
• Headache
• Indigestion

You can read more about tadalafil warnings and precautions here.

More severe but less common side effects that have been reported include:

• Chest pain
• Prolonged or painful erections
• Sudden loss of vision or hearing
• Allergic skin reactions such as hives or rashes
• Seizures

If you experience any of these side effects, immediately contact a healthcare professional.

In the rarest cases, some might experience anaphylaxis, a severe allergic reaction. 

You can read more about tadalafil's side effects here.

Who Can and Can't Take Tadalafil?

The best way to know if tadalafil is okay for you is to check with a doctor. 

First and foremost, tadalafil can only be taken by adults over 18.

You should not take tadalafil if you also take nitrates for chest pain. These are often prescribed to prevent angina (chest pain) or treat the symptoms of heart failure. The combination of nitrates and tadalafil can cause a dangerous drop in blood pressure.

Tadalafil can only be taken by adults over 18.

You should also not take tadalafil if you:

• Have had an allergic reaction to any similar medicines 
• Have serious heart or liver problems
• Recently have had a stroke or heart attack
• Have low blood pressure or high blood pressure
• Have ever lost vision because of low blood flow to your eyes

You should also check with your doctor if you:

• Have sickle cell anemia, leukemia, or multiple myeloma
• Have Peyronie's disease (curved penis or any similar issues)
• Have heart, liver, or kidney problems

Make sure to double-check if you've had any of these before taking tadalafil.

You can read more about tadalafil cost here.

Frequently Asked Questions About Tadalafil

Still have questions? Here are some of the most frequently asked questions about Tadalafil.

1- Can You Take Tadalafil Every Day?

Yes, in some cases, you can take tadalafil every day. It is often used to treat medical conditions other than ED, where it is necessary to take the medication daily.

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2- Can I Take More Than One in a Day?

No, you can only take one tablet within 24 hours.

3- Do I Need a Prescription to Get Tadalafil?

Yes, you need to have a prescription to get tadalafil. Recently, there have been several options for getting a prescription online through a virtual consultation.

4- Does Tadalafil Cure Erectile Dysfunction?

Unfortunately, tadalafil does not cure erectile dysfunction. It is only a temporary solution that helps maintain an erection by relaxing the blood vessels in the penis.

5- What's the Difference Between Cialis (Tadalafil) and Viagra (Sildenafil)?

From a distance, tadalafil and sildenafil have many similarities.

Both sildenafil and tadalafil are prescription medicines used to treat erectile dysfunction. Although they both similarly block PDE5, they have several differences.

• Sildenafil and tadalafil use different active ingredients
• Tadalafil lasts up to 36 hours, while sildenafil only lasts 4 hours
• Tadalafil is also used to treat other conditions

A 2017 review found that people with erectile dysfunction preferred tadalafil over sildenafil.

Key Takeaways

That's everything you need to know about how tadalafil works.

Even though it can sometimes feel like the end of the world when experiencing ED, it's a great relief knowing that there's a medication that can help you get your confidence back. 

We're here to bridge the gap. 

If you've ever struggled with ED, check out our products that will help you get your sexual mojo back!